Guidance on the Transfer of Select Agents and Toxins: Determining When an APHIS/CDC Form 2 is Necessary

See the chart below to determine whether a Form 2 is necessary in order to conduct a transfer.

Material to be transferred

Form 2

Material to be transferred

Inter-entity transfer of select agent or regulated amounts of toxin:

Form 2

Material to be transferred

Between two registered entities

Form 2

Yes

Material to be transferred

From an unregistered entity to a registered entity

Form 2

Yes

Material to be transferred

Imported into the U.S.

Form 2

Yes

Material to be transferred

Exported from the U.S.

*Note: The exportation of a select agent or toxin requires an export license issued by the Department of Commerce. For more information, contact the DOC Bureau of Export Administration at the Bureau of Industry and Securityexternal icon.

Form 2

No*

Material to be transferred

Select agent or regulated amounts of toxin transferred (intra-entity):

Form 2

Material to be transferred

Between two registered Principal Investigators at the same institution

Form 2

No

Material to be transferred

From an unregistered area to a registered area at the same institution

Form 2

Yes

Material to be transferred

Excluded amounts of select toxin:

Form 2

Material to be transferred

Inter- or intra-entity, either registered or unregistered entities

Form 2

No

Material to be transferred

Excluded strains of select agents listed on the FSAP website:
(Note: Attenuated strains that are not listed as excluded strains are considered select agents.)

Form 2

Material to be transferred

Inter- or intra-entity, either registered or unregistered

Form 2

No

Material to be transferred

Specimen that has been presented for diagnosis:

Form 2

Material to be transferred

That has not been identified to contain a select agent or toxin

Form 2

No

Material to be transferred

That has been identified to contain a select agent or toxin

Form 2

Yes

Material to be transferred

Proficiency samples:
(Note: At least 7 days prior to the transfer, the sender must provide a written report to FSAP detailing the select agent or toxin to be transferred and the name and address of the recipient.)

Form 2

Material to be transferred

That do not contain a select agent or toxin

Form 2

No

Material to be transferred

That contain a select agent or toxin

Form 2

No

Page last reviewed: November 19, 2020, 11:35 AM